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Antigenic Specificity | RNF2 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RNF2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 160-194 amino acids from the Central region of human RNF2. E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random X inactivation. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout |
Immunogen | n/a |
Other Names | [E3 ubiquitin-protein ligase RING2; 632-; Huntingtin-interacting protein 2-interacting protein 3; HIP2-interacting protein 3; Protein DinG; RING finger protein 1B; RING1b; RING finger protein 2; RING finger protein BAP-1; RNF2; BAP1; DING; HIPI3; RING1B] |
Gene, Accession # | [RNF2], Gene ID: 6045, NCBI: NP_009143.1, UniProt: Q99496 |
Catalog # | MBS9204258 |
Price | $165, $370 |
Order / More Info | RNF2 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Dyer M.J.S.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases. Li S.-F.,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Gregory S.G.,et al.Nature 441:315-321(2006). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. |