AMPK ALPHA 1/2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | AMPK ALPHA 1/2 |
| Clone | [34.2] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Immunohistology Frozen, ELISA (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item recognises both the alpha 1 and the alpha 2 isoforms of AMP-activated protein kinase (AMPK). AMPK is a highly conserved heterotrimeric protein kinase found in all eukaryotes. The heterotrimeric complex exists as multiple isoforms and consists of a catalytic alpha subunit, which is stabilised by non-catalytic regulatory beta- and gamma- subunits. AMPK plays a vital role in maintaining cellular energy homeostasis and is activated by rising levels of AMP under conditions of hypoxia, ischemia, exercise, low glucose levels.. AMPK may play an important role in the control of type 2 diabetes and metabolic syndromes. Recent studies suggest that AMPK functions as a suppressor of cell proliferation of both malignant and normal cells. MBS21 |
| Immunogen | Immunogen: 29 amino acid peptide within the N-terminal catalytic domain of Drosophila AMPK alpha. Buffer Solution: Phosphate buffered saline Target Species: Drosophila |
| Other Names | [5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform 1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; ACACA kinase; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK alpha 1; AMPK subunit alpha-1; HMGCR kinase; acetyl-CoA carboxylase kinase; hydroxymethylglutaryl-CoA reductase kinase; tau-protein kinase PRKAA1; protein kinase, AMP-activated, alpha 1 catalytic subunit; Acetyl-CoA carboxylase kinase (EC:2.7.11.27); ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase (EC:2.7.11.31); HMGCR kinase; Tau-protein kinase PRKAA1 (EC:2.7.11.26)], [PRKAA1; PRKAA1; AMPK; AMPKa1; AMPK1; AMPK subunit alpha-1; ACACA kinase; HMGCR kinase] |
| Gene, Accession # | Gene ID: 5562, NCBI: NP_006242.5 |
| Catalog # | MBS217351 |
| Price | $300 |
| Order / More Info | AMPK ALPHA 1/2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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