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Antigenic Specificity | PLD1 (Phospho-Thr147) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PLD1 only when phosphorylated at threonine 147. Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis.Hammond S.M., J. Biol. Chem. 272:3860-3868(1997) [PubMed: 9013646].Steed P.M., FASEB J. 12:1309-1317(1998) [PubMed: 9761774].Lopez I., J. Biol. Chem. 273:12846-12852(1998) [PubMed: 9582313]. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of threonine 147(R-H-T(p)-F-R) derived from Human PLD1. |
Other Names | [PLD 1; hPLD1; Choline phosphatase 1] |
Gene, Accession # | [PLD1], Gene ID: 5337, NCBI: NP_002653.1, UniProt: Q13393 |
Catalog # | MBS9407876 |
Price | $200, $255 |
Order / More Info | PLD1 (Phospho-Thr147) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |