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Antigenic Specificity | PTEN (Phospho Ser380/T382/T383) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-PTEN (S380/T382/T383) Polyclonal Antibody detects endogenous levels of PTEN protein only when phosphorylated at S380/T382/T383. PTEN (phosphatase and tensin homolog) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as |
Immunogen | Immunogen: Synthesized peptide derived from human PTEN around the phosphorylation site of S380/T382/T383 |
Other Names | [Rabbit PTEN (phospho Ser380/T382/T383); PTEN; MMAC1; TEP1; Phosphatidylinositol 3; 4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog] |
Gene, Accession # | [PTEN], Gene ID: 5728, NCBI: NP_000305.3, UniProt: P60484 |
Catalog # | MBS9700757 |
Price | $250, $250 |
Order / More Info | PTEN (Phospho Ser380/T382/T383) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |