PTEN (Phospho Ser380/T382/T383) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPTEN (Phospho Ser380/T382/T383)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: Phospho-PTEN (S380/T382/T383) Polyclonal Antibody detects endogenous levels of PTEN protein only when phosphorylated at S380/T382/T383. PTEN (phosphatase and tensin homolog) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as
ImmunogenImmunogen: Synthesized peptide derived from human PTEN around the phosphorylation site of S380/T382/T383
Other Names[Rabbit PTEN (phospho Ser380/T382/T383); PTEN; MMAC1; TEP1; Phosphatidylinositol 3; 4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog]
Gene, Accession #[PTEN], Gene ID: 5728, NCBI: NP_000305.3, UniProt: P60484
Catalog #MBS9700757
Price$250, $250
Order / More InfoPTEN (Phospho Ser380/T382/T383) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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