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Antigenic Specificity | SKIL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.8 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SKIL protein. The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex.TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoformshave been found for this gene. |
Immunogen | Immunogen: Fusion protein of human SKIL |
Other Names | [SNO; SnoA; SnoI; SnoN] |
Gene, Accession # | [SKIL], Gene ID: 6498, NCBI: NP_001138569.1, UniProt: P12757 |
Catalog # | MBS9416169 |
Price | $255 |
Order / More Info | SKIL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |