CRTC1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCRTC1
Clonepolyclonal
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Flow Cytometry (FC/FACS), ELISA (EIA)
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DescriptionMECT1 (also known as MucoEpidermoid Carcinoma Translocated 1) functions as a transcriptional coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites. MECT1 does not appear to modulate CREB1 DNA-binding activity but enhances the interaction of CREB1 with TAF4/TAFII-130. MECT1 translocates with MAML2 (MasterMind-Like Protein 2) to yield a fusion oncogene. t(11; 19) (q21; p13). This translocation occurs in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. The novel fusion product that results disrupts the Notch signaling pathway. The fusion protein consists of the N-terminus of MECT1 joined to the C-terminus of MAML2.
ImmunogenImmunogen: Purified recombinant fragment of human CRTC1 expressed in E. Coli.
Other Names[MECT1; TORC1; WAMTP1; FLJ14027; KIAA0616; CRTC1], [CRTC1; CRTC1; MECT1; TORC1; TORC-1; WAMTP1; TORC-1; Transducer of CREB protein 1]
Gene, Accession #[CRTC1], Gene ID: 23373, NCBI: NP_001091952.1, UniProt: Q6UUV9
Catalog #MBS850612
Price$280
Order / More InfoCRTC1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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