ERAS (N-term) (F66), 51-81 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ERAS (N-term) (F66), 51-81 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ERAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-81 amino acids from the N-terminal region of human ERAS. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Point mutations of several amino acids of human RAS, including gly12, ala59, or glu63, render the protein constitutively active. Embryonic stem cell-expressed Ras (ERAS) has serine, alanine, and asparagine at the positions corresponding to gly12, ala59, and glu63 of human RAS, suggesting that it is constitutively active.The PI3K (phosphoinositide 3-kinase) pathway is important for proliferation, survival and maintenance of pluripotency in ES cells. The PI3K pathway is activated by growth factors and cytokines includi |
| Immunogen | n/a |
| Other Names | [GTPase ERas; E-Ras; Embryonic stem cell-expressed Ras; ERAS; HRAS2; HRASP] |
| Gene, Accession # | [ERAS], Gene ID: 3266, NCBI: NP_853510.1, UniProt: Q7Z444 |
| Catalog # | MBS9207630 |
| Price | $165, $370 |
| Order / More Info | ERAS (N-term) (F66), 51-81 Antibody from MYBIOSOURCE INC. |
| Product Specific References | References for protein: 1.Kameda,T., Stem Cells 23 (10), 1535-1540 (2005) 2.Takahashi,K., Nature 423 (6939), 541-545 (2003) 3.Miyoshi,J., Nucleic Acids Res. 12 (4), 1821-1828 (1984) References for SY5Y (SH-SY5Y; ATCC#CRL-2266): 1. Ross RA, et al. Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J. Natl. Cancer Inst. 71: 741-749, 1983. [PubMed: 6137586]; 2. Biedler JL, et al. Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38: 3751-3757, 1978. [PubMed: 29704]. |
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MYBIOSOURCE INC.
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