GBP2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGBP2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: GBP2 antibody detects endogenous levels of total GBP2. Function: Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP (PubMed:8706832). Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).Subunit Structure: Homodimer; homodimerization occurs upon GTP-binding and is required for the association with membranous structures. Heterodimer with other family members, including GBP1, GBP3, GBP4 and GBP5.Post-translational Modifications: Isoprenylation is required for proper subcellular location.Similarity: Belongs to
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cell Membrane; Lipid-Anchor; Cytoplasmic Side Tissue Specificity: By IFNG/IFN-gamma during macrophage activation, and by TNF and IL1B.
Other Names[GBP 2; GTP binding protein 2; Guanine nucleotide binding protein 2; Guanylate binding protein 2 interferon inducible; HuGBP 2; HuGBP2; Interferon induced guanylate binding protein 2]
Gene, Accession #[GBP2], Gene ID: 2634, NCBI: NP_004111.2, UniProt: P32456
Catalog #MBS9604013
Price$240, $280
Order / More InfoGBP2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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