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Antigenic Specificity | GBP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GBP2 antibody detects endogenous levels of total GBP2. Function: Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP (PubMed:8706832). Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).Subunit Structure: Homodimer; homodimerization occurs upon GTP-binding and is required for the association with membranous structures. Heterodimer with other family members, including GBP1, GBP3, GBP4 and GBP5.Post-translational Modifications: Isoprenylation is required for proper subcellular location.Similarity: Belongs to |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane; Lipid-Anchor; Cytoplasmic Side Tissue Specificity: By IFNG/IFN-gamma during macrophage activation, and by TNF and IL1B. |
Other Names | [GBP 2; GTP binding protein 2; Guanine nucleotide binding protein 2; Guanylate binding protein 2 interferon inducible; HuGBP 2; HuGBP2; Interferon induced guanylate binding protein 2] |
Gene, Accession # | [GBP2], Gene ID: 2634, NCBI: NP_004111.2, UniProt: P32456 |
Catalog # | MBS9604013 |
Price | $240, $280 |
Order / More Info | GBP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |