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Antigenic Specificity | CPT1C (C-term), 596-625 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.4 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CPT1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 596-625 amino acids from the C-terminal region of human CPT1C. The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA l |
Immunogen | n/a |
Other Names | [Carnitine O-palmitoyltransferase 1; brain isoform; CPT1-B; CPT IC; Carnitine O-palmitoyltransferase I; brain isoform; CPTI-B; Carnitine palmitoyltransferase 1C; CPT1C; CATL1] |
Gene, Accession # | [CPT1C], Gene ID: 126129, NCBI: NP_001129524.1, UniProt: Q8TCG5 |
Catalog # | MBS9203315 |
Price | $165, $370 |
Order / More Info | CPT1C (C-term), 596-625 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Roomets, E., et al. Invest. Ophthalmol. Vis. Sci. 49(4):1660-1664(2008) Sierra, A.Y., et al. J. Biol. Chem. 283(11):6878-6885(2008) Price, N., et al. Genomics 80(4):433-442(2002) |