IL31R Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IL31R |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: IL31R antibody detects endogenous levels of total IL31R. Function: Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).Subunit Structure: Heterodimer with OSMR. Interacts with JAK1 and STAT3.Post-translational Modifications: N-glycosylated. |
| Immunogen | Immunogen: A synthesized peptide derived from human IL31R Subcellular Location: Cell Membrane Tissue Specificity: Expressed in CD14-and CD56-positive blood cells (PubMed:11877449). Expressed in macrophages (PubMed:16461143, PubMed:18439099). Expressed in keratinocytes (PubMed:21261663). Expressed in a subset of dorsal root ganglia neurons (at protein level) (PubMed:24373353). Expressed at low levels in testis, ovary, brain, prostate, placenta, thymus, bone marrow, trachea and skin (PubMed:151848 |
| Other Names | [Class I cytokine receptor; CRL 3; CRL; CRL3; Cytokine receptor like 3; Cytokine receptor-like 3; GLM R; GLM-R; GLMR; Gp130 like monocyte receptor; GP130 like receptor; Gp130-like monocyte receptor; Gp130-like receptor; GPL; HGLM R; HGLM-R; HGLMR; IL 31 receptor subunit alpha; IL 31R subunit alpha; IL 31RA; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; IL31 receptor subunit alpha; IL31R subunit alpha; IL31R_HUMAN; IL31RA; Interleukin 31 receptor A; interleukin 31 receptor subunit alpha; Interleukin-31 receptor subunit alpha; MGC125346; PLCA 2; PLCA2; PRO21384; Soluble type I cytokine receptor CRL3; ZcytoR17] |
| Gene, Accession # | [IL31RA], Gene ID: 133396, NCBI: NP_001229565.1, UniProt: Q8NI17 |
| Catalog # | MBS9602973 |
| Price | $240, $280 |
| Order / More Info | IL31R Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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