KANK2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKANK2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, bovine, sheep, dog, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: KANK2 Antibody detects endogenous levels of KANK2. Description: Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500). May be involved in promotion of cell proliferation (By similarity).Post Tra
ImmunogenImmunogen: A synthesized peptide derived from human KANK2. Tissue Specificity: Strongly expressed in cervix, colon, heart, kidney and lung. Expressed in kidney glomerular podocytes and mesangial cells (at protein level).
Other Names[ANKRD25; Ankyrin repeat domain 25; Ankyrin repeat domain containing protein 25; DKFZp434N161; FLJ20004; KANK 2; KANK2; KIAA1518; Kidney ankyrin repeat containing protein 2; KN motif and ankyrin repeat domain containing protein 2; KN motif and ankyrin repeat domains 2; Matrix remodeling associated protein 3; Matrix remodelling associated 3; MGC119707; MXRA3; SIP; SRC 1 interacting protein; SRC interacting protein; SRC1 interacting protein]
Gene, Accession #[KANK2], Gene ID: 25959, NCBI: NP_001129663.1, UniProt: Q63ZY3
Catalog #MBS9611852
Price$240, $280
Order / More InfoKANK2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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