Edit |   |
---|---|
Antigenic Specificity | KANK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, sheep, dog, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: KANK2 Antibody detects endogenous levels of KANK2. Description: Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500). May be involved in promotion of cell proliferation (By similarity).Post Tra |
Immunogen | Immunogen: A synthesized peptide derived from human KANK2. Tissue Specificity: Strongly expressed in cervix, colon, heart, kidney and lung. Expressed in kidney glomerular podocytes and mesangial cells (at protein level). |
Other Names | [ANKRD25; Ankyrin repeat domain 25; Ankyrin repeat domain containing protein 25; DKFZp434N161; FLJ20004; KANK 2; KANK2; KIAA1518; Kidney ankyrin repeat containing protein 2; KN motif and ankyrin repeat domain containing protein 2; KN motif and ankyrin repeat domains 2; Matrix remodeling associated protein 3; Matrix remodelling associated 3; MGC119707; MXRA3; SIP; SRC 1 interacting protein; SRC interacting protein; SRC1 interacting protein] |
Gene, Accession # | [KANK2], Gene ID: 25959, NCBI: NP_001129663.1, UniProt: Q63ZY3 |
Catalog # | MBS9611852 |
Price | $240, $280 |
Order / More Info | KANK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |