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Antigenic Specificity | CD284 |
Clone | [2E12C8] |
Host Species | Mouse |
Reactive Species | mouse, rat |
Isotype | IgG |
Format | affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1.8 mg/mL |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described. |
Immunogen | Immunogen: Recombinant protein corresponding to Mouse TLR4 |
Other Names | [ARMD10; CD284; CD284 antigen; Homolog of Drosophila toll; hToll; TLR 4; TLR4; TLR4; TOLL; Toll like receptor 4; Toll-like receptor 4] |
Gene, Accession # | [CD284], Gene ID: 21898, NCBI: NP_067272.1, UniProt: Q9QUK6 |
Catalog # | MBS2556247 |
Price | $150, $225, $360 |
Order / More Info | CD284 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |