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Antigenic Specificity | Mouse CD274 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cyometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1 (PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 family expressed on activated lymphoid cells. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tum |
Immunogen | Immunogen: Recombinant Mouse PD-L1/B7-H1/CD274 protein Buffer: 0.2 mum filtered solution in PBS |
Other Names | [CD274, partial; Programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; CD274 molecule; B7 homolog 1; B7-H1; CD_antigen: CD274] |
Gene, Accession # | [CD274 ], Gene ID: 29126 |
Catalog # | MBS2544430 |
Price | $215, $330, $500 |
Order / More Info | Mouse CD274 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |