RAC1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRAC1
Clone[1301CT276.121.104]
Host SpeciesMouse
Reactive Specieshuman, rat (predicted reactivity: bovine, mouse)
IsotypeIgG2b
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)
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DescriptionThis antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from human. Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Stimulates
Immunogenn/a
Other Names[Ras-related C3 botulinum toxin substrate 1; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1; RAC1; TC25]
Gene, Accession #[RAC1], Gene ID: 5879, NCBI: NP_008839.2, UniProt: P63000
Catalog #MBS9200589
Price$165, $370
Order / More InfoRAC1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesDidsbury J.,et al.J. Biol. Chem. 264:16378-16382(1989). Drivas G.T.,et al.Mol. Cell. Biol. 10:1793-1798(1990). Matos P.,et al.Biochem. Biophys. Res. Commun. 277:741-751(2000). Jordan P.,et al.Oncogene 18:6835-6839(1999). Schnelzer A.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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