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Antigenic Specificity | FLIP |
Clone | [AT8B12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FLIP, also known as CASP8 and FADD-like apoptosis regulator (CFLAR), contains two death effector domains (DEDs) and a caspase-like domain. FLIP may play a crucial role between cell survival and cell death pathway in mammalian cells and interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (death receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (tumor necrosis factor receptor 1). |
Immunogen | Immunogen: Recombinant human FLIP (1-480aa) purified from E. coli |
Other Names | [CASP8 and FADD-like apoptosis regulator isoform 1; CFLAR; CASH; CASP8AP1; CLARP; MRIT; Caspase homolog; Caspase-eight-related protein; Casper; Caspase-like apoptosis regulatory protein; Cellular FLICE-like inhibitory protein; FLAME-1; Inhibitor of FLICE; I-FLICE; MACH-related inducer of toxicity], [CFLAR; CFLAR; CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1; CASH; CASP8AP1; CLARP; MRIT; CASH; Casper; CLARP; c-FLIP; FLAME-1; I-FLICE; MRIT] |
Gene, Accession # | [FLIP], Gene ID: 8837, NCBI: NP_003870, UniProt: O15519 |
Catalog # | MBS200126 |
Price | $240, $315 |
Order / More Info | FLIP Antibody from MYBIOSOURCE INC. |
Product Specific References | Yu JW, Shi Y., (2008) Oncogene. 27 (48):6216-27; Du C, et al., (2005) Kidney Int. 67 (4):1397-409 |