FLIP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFLIP
Clone[AT8B12]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, k
FormatProtein G purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionFLIP, also known as CASP8 and FADD-like apoptosis regulator (CFLAR), contains two death effector domains (DEDs) and a caspase-like domain. FLIP may play a crucial role between cell survival and cell death pathway in mammalian cells and interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (death receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (tumor necrosis factor receptor 1).
ImmunogenImmunogen: Recombinant human FLIP (1-480aa) purified from E. coli
Other Names[CASP8 and FADD-like apoptosis regulator isoform 1; CFLAR; CASH; CASP8AP1; CLARP; MRIT; Caspase homolog; Caspase-eight-related protein; Casper; Caspase-like apoptosis regulatory protein; Cellular FLICE-like inhibitory protein; FLAME-1; Inhibitor of FLICE; I-FLICE; MACH-related inducer of toxicity], [CFLAR; CFLAR; CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1; CASH; CASP8AP1; CLARP; MRIT; CASH; Casper; CLARP; c-FLIP; FLAME-1; I-FLICE; MRIT]
Gene, Accession #[FLIP], Gene ID: 8837, NCBI: NP_003870, UniProt: O15519
Catalog #MBS200126
Price$240, $315
Order / More InfoFLIP Antibody from MYBIOSOURCE INC.
Product Specific ReferencesYu JW, Shi Y., (2008) Oncogene. 27 (48):6216-27; Du C, et al., (2005) Kidney Int. 67 (4):1397-409
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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