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Antigenic Specificity | Frizzled 8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes endogenous levels of Frizzled 8 protein. Frizzled 8 is a receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. |
Immunogen | Immunogen: Frizzled 8 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Frizzled 8 as the immunogen |
Other Names | [Purified Frizzled 8; Frizzled 8; Frizzled 8; Frizzled-8; Fz-8; hFz8] |
Gene, Accession # | [Fz-8], Gene ID: 8325, UniProt: Q9H461 |
Catalog # | MBS5315209 |
Price | $270 |
Order / More Info | Frizzled 8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |