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Antigenic Specificity | BFAR (BAR) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BAR (bifunctional apoptosis regulator) is a multidomain protein that was originally identified as an inhibitor of Bax-induced apoptosis. BAR is in anchored in intracellular membranes and is thought to be a scaffold protein that may bridge components of both extrinsic and intrinsic apoptosis pathways through its antiapoptotic domains: 1. BAR contains a DED (death effector domain)-like protein interaction domain that suppresses death receptor apoptosis signaling pathways.BAR is highly expressed in the brain and expression patterns as well as functional data with neuronal cell lines suggest that BAR is involved in regulating neuronal survival. Additionally, subcellular localization studies indicate that BAR predominantly localizes to the endop |
Immunogen | Immunogen Information: A synthetic peptide of BFAR (BAR) protein (amino acids 3-21 EPQKSYVNTMDLERDEPLK) was used as the immunogen for this antibody |
Other Names | [BFAR; BAR; RNF47; Beta-2 adrenoreceptor; to BFAR (BAR); BFAR (BAR); BFAR (BAR)], [BFAR; BFAR; BAR; RNF47; BAR; RNF47] |
Gene, Accession # | [BFAR], Gene ID: 51283, NCBI: Q9NZS9.1, UniProt: Q9NZS9 |
Catalog # | MBS668547 |
Price | $270 |
Order / More Info | BFAR (BAR) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |