Human IL-21 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman IL-21
Clone[SB134f]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
Formatunconjugated
Size0.5 mg
Concentrationn/a
ApplicationsELISA
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DescriptionReacts with human IL-21. Interleukin-21 (IL-21) is a four helical bundle type I cytokine1. The mature form of human IL-21 is a 131 amino acid protein.4 IL-21 is expressed primarily by NKT and CD4+ T cells, particularly the inflammatory Th17 subset and has pleiotropic effects on both innate and adaptive immune responses. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocyte lineages, costimulation of Tcells and augmentation of antitumor activity of CD8+ T cells.2, 3 Recent studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation and suppresses Foxp3 expression, and serves as a target for treat
ImmunogenImmunogen: Recombinant human IL-21. Characterization: To ensure acceptable performance, each batch of product is tested by ELISA to conform to characteristics of a standard reference reagent.
Other Names[Mouse Human Interleukin-21 (IL-21)], [IL21; IL21; Za11; IL-21; IL-21]
Gene, Accession #Gene ID: 59067, NCBI: NP_001193935.1, UniProt: Q9HBE4
Catalog #MBS670185
Price$265
Order / More InfoHuman IL-21 Antibody from MYBIOSOURCE INC.
Product Specific References1) Rosanne Spolski and Warren J. Leonard (2008). Annu Rev Immunol 29:57-79.2) Ettinger, R., et al. (2005). J. Immunol. 175:7867-7879.3) Kuchen, S., et al. (2007). J. Immunol. 179:5886-5896.4) Parrish-Novak, J. et al. (2000). Nature. 408:57-63.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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