p53 (T55), 33-62 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | p53 (T55), 33-62 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.3 |
| Applications | Western Blot (WB), ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This p53 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from human p53. Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor supp |
| Immunogen | n/a |
| Other Names | [Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53; TP53; P53] |
| Gene, Accession # | [TP53], Gene ID: 7157, NCBI: NP_000537.3, UniProt: P04637 |
| Catalog # | MBS9206346 |
| Price | $165, $370 |
| Order / More Info | p53 (T55), 33-62 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Blanchette, P., et al., Mol. Cell. Biol. 24(21):9619-9629 (2004). Adachi, K., et al., Oncogene 23(47):7791-7798 (2004). Zhang, Y., et al., J. Biol. Chem. 279(41):42545-42551 (2004). Anazawa, Y., et al., Oncogene 23(46):7621-7627 (2004). Montagnoli, A., et al., Cancer Res. 64(19):7110-7116 (2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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