Edit |   |
---|---|
Antigenic Specificity | ITGAL (Center), 722-751 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ITGAL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 722-751 amino acids from the Central region of human ITGAL. ITGAL encodes the integrin alpha L chain. Integrins areheterodimeric integral membrane proteins composed of an alpha chainand a beta chain. This I-domain containing alpha integrin combineswith the beta 2 chain (ITGB2) to form the integrin lymphocytefunction-associated antigen-1 (LFA-1), which is expressed on allleukocytes. LFA-1 plays a central role in leukocyte intercellularadhesion through interactions with its ligands, ICAMs 1-3(intercellular adhesion molecules 1 through 3), and also functionsin lymphocyte costimulatory signaling. Two transcript |
Immunogen | n/a |
Other Names | [Integrin alpha-L; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; CD11a; ITGAL; CD11A] |
Gene, Accession # | [ITGAL], Gene ID: 3683, NCBI: NP_001107852.1, UniProt: P20701 |
Catalog # | MBS9212282 |
Price | $165, $370 |
Order / More Info | ITGAL (Center), 722-751 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Kuwano, Y., et al. Blood 116(4):617-624(2010) Ghannam, S., et al. J. Immunol. 185(1):302-312(2010) Quist, S.R., et al. Acta Derm. Venereol. 90(4):429-430(2010) Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010) |