Human Membrane cofactor protein Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Membrane cofactor protein |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | fluorescein (FITC) conjugate |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46. |
| Immunogen | Immunogen: Recombinant human Membrane cofactor protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7056 / sc-9098 |
| Other Names | [TLX; Trophoblast leukocyte common antigen; CD46; MCP; MIC10], [CD46; CD46; MCP; TLX; AHUS2; MIC10; TRA2.10; MCP; MIC10] |
| Gene, Accession # | [CD46], Gene ID: 4179, NCBI: NP_002380.3, UniProt: P15529 |
| Catalog # | MBS968979 |
| Price | $160, $235 |
| Order / More Info | Human Membrane cofactor protein Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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