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Antigenic Specificity | ENSA (Center), 39-66 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: bovine, chicken, zebrafish, porcine, rat, Xenopus) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ENSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human ENSA. ENSA belongs to a highlyconserved cAMP-regulated phosphoprotein (ARPP) family. This proteinwas identified as an endogenous ligand for the sulfonylureareceptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of theATP-sensitive potassium (KATP) channel, which is located on theplasma membrane of pancreatic beta cells and plays a key role inthe control of insulin release from pancreatic beta cells. Thisprotein is thought to be an endogenous regulator of KATP channels.In vitro studies have demonstrated that this protein modulatesinsulin secretion through |
Immunogen | n/a |
Other Names | [Alpha-endosulfine; ARPP-19e; ENSA] |
Gene, Accession # | [ENSA], Gene ID: 2029, NCBI: NP_004427.1, UniProt: O43768 |
Catalog # | MBS9213170 |
Price | $165, $370 |
Order / More Info | ENSA (Center), 39-66 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Olsen, J.V., et al. Cell 127(3):635-648(2006) Olsen, J.V., et al. Cell 127(3):635-648(2006) Gabrielsson, B.G., et al. Mol. Cell. Biochem. 258 (1-2), 65-71 (2004) : Thameem, F., et al. Mol. Genet. Metab. 81(1):16-21(2004) |