beta-Dystroglycan (Tyr-892), phospho-specific Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-beta-Dystroglycan (Tyr-892), phospho-specific antibody, protein, ELISA kits.
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| Antigenic Specificity | beta-Dystroglycan (Tyr-892), phospho-specific |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, rat, mouse |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects a 43 kDa* protein on SDS-PAGE immunoblots of human HepG2 or HeLa cells treated with pervanadate, but not in control cells. Dystroglycans are essential elements of the neuromuscular junction (NMJ). The gene for dystroglycan is expressed as a precursor protein that is post-translationally cleaved into a 156 kDa extracellular peripheral membrane protein called a-dystroglycan and a 43 kDa transmembrane protein, b-dystroglycan. The latter protein contains a PPxY motif that promotes binding to WW domain-containing proteins, such as utrophin and dystrophin. Phosphorylation at tyrosine 892 within the PPxY motif may regulate c-Src interactions with beta-dystroglycan, as well as inhibit interactions with WW domain proteins. In sk |
| Immunogen | Immunogen: Clone (M117) was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 892 of humandystroglycan. This peptide sequence has high homology to the conserved tyrosine site in rat and mouse dystroglycan. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS470003 |
| Price | $385 |
| Order / More Info | beta-Dystroglycan (Tyr-892), phospho-specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | • James, M. et al. (2000) J Cell Sci. 113(Pt 10):1717-1726.• Sotgia, F. et al. (2003) Biochem. 42(23):7110-7123. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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