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Antigenic Specificity | Musashi |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia and Parkinson's. The presence of Msi-1 in a significant percentage of neurons containing cytoplasmic inclusions in 2 other neurodegenerative diseases Alzheimer's disease and Pick disease suggests that it may play a role in the pathogenesis of these neurodegenerative disorders. Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play be an vital role in the development of several types of carcinoma such a |
Immunogen | Immunogen: APQPGLASPDSPHDPCK |
Other Names | [Musashi; RNA-binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 1; musashi RNA binding protein 1], [MSI1; MSI1; Musashi-1] |
Gene, Accession # | Gene ID: 4440, NCBI: BAA33962.1 |
Catalog # | MBS555314 |
Price | $315 |
Order / More Info | Musashi Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |