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Antigenic Specificity | CHRNA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.9 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CHRNA2 protein. Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autoso |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human cholinergic receptor, nicotinic, alpha 2 (neuronal) |
Other Names | [ACHA2; CHRNA2; Neuronal acetylcholine receptor subunit alpha-2] |
Gene, Accession # | [CHRNA2], Gene ID: 1135, NCBI: NP_000733.2, UniProt: Q15822 |
Catalog # | MBS9404514 |
Price | $255 |
Order / More Info | CHRNA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |