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Antigenic Specificity | AP2M1 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AP2M1 Antibody: The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exis |
Immunogen | Immunogen: AP2M1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human AP2M1. Buffer: AP2M1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [AP2M1; mu2; AP50; CLAPM1; KIAA0109; AP-2 complex subunit mu; AP-2 mu chain; adaptor-related protein complex 2, mu 1 subunit], [AP2M1; AP2M1; mu2; AP50; CLAPM1; CLAPM1; KIAA0109] |
Gene, Accession # | [AP2M1], Gene ID: 1173, NCBI: NP_004059, UniProt: Q96CW1 |
Catalog # | MBS151264 |
Price | $375 |
Order / More Info | AP2M1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |