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Antigenic Specificity | HDAC5 (Phospho Ser498) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-HDAC5 (S498) Polyclonal Antibody detects endogenous levels of HDAC5 protein only when phosphorylated at S498. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 5 encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependen |
Immunogen | Immunogen: Synthesized peptide derived from human HDAC5 around the phosphorylation site of S498 |
Other Names | [Rabbit HDAC5 (phospho Ser498); HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9] |
Gene, Accession # | [HDAC5], Gene ID: 10014, NCBI: NP_001015053.1, UniProt: Q9UQL6 |
Catalog # | MBS9701081 |
Price | $130, $220, $325 |
Order / More Info | HDAC5 (Phospho Ser498) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |