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Antigenic Specificity | Human F8 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Coagulation Factor VIII, also known as FVIII and F8, is a member of the multicopper oxidase family. Coagulation Factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. It contains 3 F5/8 type A domains, 2 F5/8 type C domains and 6 plastocyanin-like domains. FVIII is synthesized in the liver, and perhaps in other tissues. It is a coagulation cofactor which circulates bound to von Willebrand factor and is part of the intrinsic coagulation pathway. It is a macromolecular complex composed of two separate entities, one of which, when deficient, results in hemophilia A, and the other, when deficient, results in von Willebrand's disease. Hemophilia A is a disorder of bl |
Immunogen | Immunogen: Recombinant Human Coagulation Factor VIII/FVIII/F8 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [F8] |
Gene, Accession # | [F8 ] |
Catalog # | MBS2544424 |
Price | $215, $330, $500 |
Order / More Info | Human F8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |