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Antigenic Specificity | MAP1LC3 B (MAP1LC3B, APG8b) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAP1LC3B is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. MAP1LC3B is probably involved in formation of autophagosomal vacuoles (autophagosomes). SUBCELLULAR LOCATION: LC3-I: Cytoplasm. LC3-II: Intracytoplasmic membrane; lipid-anchor. Cytoplasmic vesicle; autophagosome; autophagosomal membrane; lipid-anchor. LC3-II binds to the autophagic membranes. TISSUE SPECIFICITY: Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver. PTM: The precursor molecule is cleaved by APG4B/ATG4B to form LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form LC3-II. SIMILARITY: B |
Immunogen | Immunogen: A synthetic peptide corresponding to the N-terminal of human MAP1LC3 B (MAP1LC3B, APG8b) protein conjugated to Blue Carrier Protein has been used as the immunogen. The peptide is homologous with the corresponding sequence derived from mouse and rat MAP1LC3 B (MAP1LC3B, APG8b) protein. Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide. |
Other Names | [MAP1LC3B; APG8b] |
Gene, Accession # | [MAP1LC3 B] |
Catalog # | MBS4152729 |
Price | $515 |
Order / More Info | MAP1LC3 B (MAP1LC3B, APG8b) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |