Phospho-Caspase 8 (Ser347) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Caspase 8 (Ser347)
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: Phospho-Caspase 8 (Ser347) Antibody detects endogenous levels of Caspase 8 only when phosphorylated at Serine 347. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits.
ImmunogenImmunogen: A synthesized peptide derived from human Caspase 8 around the phosphorylation site of Serine 347
Other Names[Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; Caspase-8 precursor; EC 3.4.22.-; EC 3.4.22.61; FADD-homologous ICE/CED-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; ICE8; MACH; MCH5; MORT1-associated CED-3 homolog]
Gene, Accession #Gene ID: 841, NCBI: NP_001073593.1, UniProt: Q14790
Catalog #MBS8511623
Price$290
Order / More InfoPhospho-Caspase 8 (Ser347) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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