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Antigenic Specificity | Phospho-Caspase 8 (Ser347) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Caspase 8 (Ser347) Antibody detects endogenous levels of Caspase 8 only when phosphorylated at Serine 347. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. |
Immunogen | Immunogen: A synthesized peptide derived from human Caspase 8 around the phosphorylation site of Serine 347 |
Other Names | [Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; Caspase-8 precursor; EC 3.4.22.-; EC 3.4.22.61; FADD-homologous ICE/CED-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; ICE8; MACH; MCH5; MORT1-associated CED-3 homolog] |
Gene, Accession # | Gene ID: 841, NCBI: NP_001073593.1, UniProt: Q14790 |
Catalog # | MBS8511623 |
Price | $290 |
Order / More Info | Phospho-Caspase 8 (Ser347) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |