Edit |   |
---|---|
Antigenic Specificity | HTRA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total HTRA2 protein. This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determine |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human HTRA2. |
Other Names | [OMI; PARK13; PRSS25] |
Gene, Accession # | [HTRA2], Gene ID: 27429, NCBI: NP_037379.1, UniProt: O43464 |
Catalog # | MBS9401757 |
Price | $255 |
Order / More Info | HTRA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |