LIF Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | LIF |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Leukemia Inhibitory Factor (LIF) is a 20 kDa pleiotrophic factor belonging to the IL6 superfamily of cytokines (1). LIF is expressed in a number of tissues and cell types. The LIF receptor is a heterodimer comprised of LIFR (gp190) and gp130, a common signal transducer for IL6type cytokines (1). Depending on cell type and context, LIF/LIFR can activate Erk, PI3K, and Jak1/Stat1/3 pathways (1,2). LIF has a diverse array of biological activities. Murine embryonic stem cells are dependent on LIF for pluripotency and selfrenewal in vitro (1). Exerciseinduced LIF secretion in muscle induces myoblast proliferation, suggesting that LIF may play a role in exerciseinduced muscle hypertrophy (2). LIF also negatively regulates Th2 and Th17 cell differ |
| Immunogen | Immunogen: A synthetic peptide of human LIF |
| Other Names | [LIF; LIF; HILDA; Leukemia inhibitory factor; Differentiationstimulating factor; Melanomaderived LPL inhibitor; INN=Emfilermin; Flags: Precursor], [LIF; LIF; CDF; DIA; HILDA; MLPLI; HILDA; LIF; D factor; MLPLI] |
| Gene, Accession # | Gene ID: 3976, NCBI: NP_001244064.1, UniProt: P15018 |
| Catalog # | MBS127798 |
| Price | $200, $275, $430 |
| Order / More Info | LIF Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Mathieu, M.E. et al. (2012) Stem Cell Rev 8, 115. 2. Broholm, C. and Pedersen, B.K. (2010) Exerc Immunol Rev 16, 7785 3. Cao, W. et al. (2011) Immunity 35, 27384. 4. Ullah, U. et al. (2012) Sci Rep 2, 464. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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