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Antigenic Specificity | TRPV6 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TRPV6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 352-385 amino acids from the Central region of human TRPV6. Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin- dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel proper |
Immunogen | n/a |
Other Names | [Transient receptor potential cation channel subfamily V member 6; TrpV6; CaT-like; CaT-L; Calcium transport protein 1; CaT1; Epithelial calcium channel 2; ECaC2; TRPV6; ECAC2] |
Gene, Accession # | [TRPV6], Gene ID: 55503, NCBI: NP_061116.5, UniProt: Q9H1D0 |
Catalog # | MBS9205143 |
Price | $165, $370 |
Order / More Info | TRPV6 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Peng J.-B.,et al.Biochem. Biophys. Res. Commun. 278:326-332(2000). Wood R.J.,et al.BMC Physiol. 1:11-11(2001). Peng J.-B.,et al.Genomics 76:99-109(2001). Wissenbach U.,et al.J. Biol. Chem. 276:19461-19468(2001). Peng J.-B.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. |