Human CD28: Low Endotoxin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD28: Low Endotoxin |
| Clone | [YTH913.12] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Functional Assays (FN) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rat anti Human CD28 antibody, clone YTH913.12 recognizes human CD28, a ~44kDa single pass type 1 trans-membrane protein expressed as a homodimer on a major subset of human T-cells (Thompson et al. 1989), responsible for activation of these cells via interaction with the TCR. CD28 is involved in the tuning of the T-cell for activation via TCR, lowering the threshold for activation from around 8000 triggered TCRs to approximately 1500 (Viola et al.1996). CD28 along with CD152, also known as CTLA-4 acts as a co-receptor for the co-stimulatory molecules CD80 and CD86 (Azuma et al. 1993). CD28 offers a positive stimulatory role on ligation of CD80 and CD86 while CTLA-4 offers a negative feedback signal preventing CD28 mediated T-cell activation |
| Immunogen | n/a |
| Other Names | [T-cell-specific surface glycoprotein CD28 isoform 2; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28; CD28 antigen; CD28 molecule; TP44; CD_antigen: CD28], [CD28; CD28; Tp44] |
| Gene, Accession # | [CD28], Gene ID: 940, NCBI: NP_001230006.1, UniProt: P10747 |
| Catalog # | MBS211263 |
| Price | $675 |
| Order / More Info | Human CD28: Low Endotoxin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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