Human CD74 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD74 |
| Clone | [Bu45] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 0.1 mg |
| Concentration | IgG concentration 0.1mg/ml |
| Applications | Flow cytometry (FC/FACS)* |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti Human CD74 antibody, clone Bu45 recognizes human CD74, a type II transmembrane protein, which is also known as the MHC class II associated invariant chain. The Bu45 antibody recognizes 33, 35 and 41 kD isoforms of CD74. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, dendritic cells and by various types of carcinoma. Expression of CD74 is primarily intracellular with moderate expression at the cell surface of B cells and monocytes. The Bu45 antibody binds to an epitope within the extracytoplasmic domain of the CD74 molecule, which is dista |
| Immunogen | Immunogen: B lymphoblastoid cell line HFB1. Fusion Partners: Spleen cells from immunised mice were fused with cells of the Ag8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
| Other Names | [HLA class II histocompatibility antigen gamma chain isoform c; HLA class II histocompatibility antigen gamma chain; HLA class II histocompatibility antigen gamma chain; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); HLA-DR antigens-associated invariant chain; HLA-DR-gamma; Ia-associated invariant chain; MHC HLA-DR gamma chain; gamma chain of class II antigens; p33; CD74 molecule, major histocompatibility complex, class II invariant chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD_antigen: CD74], [CD74; CD74; II; DHLAG; HLADG; Ia-GAMMA; DHLAG; Ii] |
| Gene, Accession # | [CD74], Gene ID: 972, NCBI: NP_001020329.1, UniProt: P04233 |
| Catalog # | MBS210988 |
| Price | $370 |
| Order / More Info | Human CD74 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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