HP-1gamma Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHP-1gamma
Clone[6F7-6A3-2B10]
Host SpeciesMouse
Reactive Specieshuman, rat, mouse
IsotypeIgG1
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSeems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1. Mediates the recruitement
ImmunogenImmunogen: Purified recombinant protein expressed in E Coli.
Other Names[CBX3; Chromobox homolog 3; HECH; HP1 gamma; CBX3]
Gene, Accession #[HP-1gamma], Gene ID: 11335, NCBI: NP_009207.2, UniProt: Q13185
Catalog #MBS8539826
Price$280
Order / More InfoHP-1gamma Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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