Amyloid Precursor Proteins Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAmyloid Precursor Proteins
Clonepolyclonal
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC)
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DescriptionAlzheimer's disease, the most common cause of dementia in the elderly, exists in both familial and sporadic forms. Genetic studies have identified three genes; beta-amyloid precursor protein (APP), Presenilin 1 and Presenilin 2 which, when mutated, can cause familial forms of Alzheimer's disease. APP and APP-like proteins are transmembrane glycoproteins with a similar modular domain structure. APP-228 has been raised to the extracellular portion of APP between the Kunitz protease inhibitor domain and the beta amyloid region. This region shows the least homology with the APP-like proteins. APP-228 and does not cross-react with APP-like proteins. APP reacts with large pyramidal cells as well as smaller neurons, astrocytes and microglia. APP 2
ImmunogenImmunogen: Prokaryotic recombinant fusion protein corresponding to the extracellular protein of APP between the Kunitz protease inhibitor domain and the beta amyloid region.
Other Namesn/a
Gene, Accession #[APP]
Catalog #MBS555076
Price$265
Order / More InfoAmyloid Precursor Proteins Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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