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Antigenic Specificity | CD34 (Hematopoietic Stem Cell & Endothelial Marker) |
Clone | [HPCA1/1806R] |
Host Species | Rabbit |
Reactive Species | human, rat. |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity. |
Immunogen | Immunogen: Recombinant full-length human HPCA1 protein Cellular Localization: Cell Surface |
Other Names | [Hematopoietic Progenitor Cell Antigen; HPCA1; Mucosialin] |
Gene, Accession # | [CD34], Gene ID: 947, NCBI: NP_001020280.1, UniProt: P28906 |
Catalog # | MBS4380346 |
Price | $190, $340, $340 |
Order / More Info | CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Sato T et al. Blood 94:2548-2554 (1999). Felshow DM et al. Blood 97:3768-3775 (2001). |