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Antigenic Specificity | MAGA6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MAGA6 antibody detects endogenous levels of total MAGA6. Function: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.Subunit Structure: Interacts with TRIM28. |
Immunogen | Immunogen: A synthesized peptide derived from human MAGA6 Tissue Specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. |
Other Names | [Cancer/testis antigen 1.6; Cancer/testis antigen family 1, member 6; CT1.6; MAGA6_HUMAN; MAGE 3b; MAGE 6 antigen; MAGE-6 antigen; MAGE3B; MAGE3B antigen; MAGE6; MAGEA6; Melanoma antigen family A 6; Melanoma associated antigen 6; Melanoma-associated antigen 6] |
Gene, Accession # | [MAGA6], Gene ID: 4105, NCBI: NP_005354.1, UniProt: P43360 |
Catalog # | MBS9602890 |
Price | $240, $280 |
Order / More Info | MAGA6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |