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Antigenic Specificity | Phospho-RhoA (Ser188) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-RhoA (Ser188) antibody detects endogenous levels of RhoA only when phosphorylated at Serine 188. Function: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and dis |
Immunogen | Immunogen: A synthesized peptide derived from human RhoA around the phosphorylation site of Serine 188 Subcellular Location: Cell Membrane. Cytoplasm > Cytoskeleton. Predicted Cross Reactivity: Pig, Bovine, Sheep, Dog Similarity: Pig (100%), Bovine (100%), Sheep (100%), Dog (100%) |
Other Names | [Aplysia ras related homolog 12; ARH12; ARHA; H 12; H12; Oncogene RHO H12; Ras homolog family member A; Ras homolog gene family member A; Rho A; Rho cDNA clone 12; RHO H12; RHO12; RHOA; RHOA_HUMAN; RHOH12; Small GTP binding protein Rho A; Transforming protein Rho A; Transforming protein RhoA] |
Gene, Accession # | [RhoA], Gene ID: 387, NCBI: NP_001300870.1, UniProt: P61586 |
Catalog # | MBS9601121 |
Price | $240, $280 |
Order / More Info | Phospho-RhoA (Ser188) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |