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Antigenic Specificity | HNMT (N-term), 29-58 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human HNMT. In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. |
Immunogen | n/a |
Other Names | [Histamine N-methyltransferase; HMT; HNMT] |
Gene, Accession # | [HNMT], Gene ID: 3176, NCBI: NP_001019245.1, UniProt: P50135 |
Catalog # | MBS9214128 |
Price | $165, $370 |
Order / More Info | HNMT (N-term), 29-58 Antibody from MYBIOSOURCE INC. |
Product Specific References | Aksoy, S., et al., Biochem. Biophys. Res. Commun. 219(2):548-554 (1996). |