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Antigenic Specificity | ADRA2C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, w |
Immunogen | Immunogen: Recombinant fusion protein of human ADRA2C. |
Other Names | [ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR] |
Gene, Accession # | [ADRA2C], Gene ID: 152, NCBI: NP_000674.2, UniProt: P18825 |
Catalog # | MBS8571594 |
Price | $280 |
Order / More Info | ADRA2C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |