ATG4C Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ATG4C |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Predicted molecular weight at ~52.5 kDa. Observed molecular weights at ~45-60 kDa. ATG4C belongs to the peptidase C54 family. It is a cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. It also has an activity of delipid |
| Immunogen | Immunogen: Synthetic peptide from the N-terminal of human ATG4C |
| Other Names | [Rabbit Human ATG4C; APG4 autophagy 4 homolog C; APG4 C; Atg4c; AUTL1; Autophagin 3; Cysteine protease ATG4C] |
| Gene, Accession # | [ATG4C], Gene ID: 84938, NCBI: NP_116241.2, UniProt: Q96DT6 |
| Catalog # | MBS8004703 |
| Price | $515 |
| Order / More Info | ATG4C Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Li M., et al. (2011) J Biol Chem. 286: 7327-7338. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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