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Antigenic Specificity | ITGA7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required |
Immunogen | Immunogen: Recombinant Human Integrin alpha-7 protein (175-283AA) |
Other Names | [Integrin alpha-7; Integrin alpha-7 heavy chainIntegrin alpha-7 light chainIntegrin alpha-7 70 kDa form; ITGA7; UNQ406/PRO768] |
Gene, Accession # | [ITGA7], Gene ID: 3679, NCBI: NP_001138468.1, UniProt: Q13683 |
Catalog # | MBS7109168 |
Price | $160, $235 |
Order / More Info | ITGA7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |