Edit |   |
---|---|
Antigenic Specificity | AIRE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). |
Immunogen | Immunogen: Recombinant protein of human AIRE (NP 000374.1). |
Other Names | [autoimmune regulator; Autoimmune regulator; autoimmune regulator; autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein] |
Gene, Accession # | [AIRE], Gene ID: 326, NCBI: NP_000374.1, UniProt: O43918 |
Catalog # | MBS8568874 |
Price | $280 |
Order / More Info | AIRE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |