Edit |   |
---|---|
Antigenic Specificity | GRN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual act |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [GEP; GP88; PEPI; PGRN; CLN11; PCDGF] |
Gene, Accession # | [GRN], Gene ID: 2896, NCBI: P28799.2, UniProt: P28799 |
Catalog # | MBS9127503 |
Price | $200, $275, $430 |
Order / More Info | GRN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |