IGF-IIR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIGF-IIR
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA)
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DescriptionSpecificity: IGF-IIR Polyclonal Antibody detects endogenous levels of IGF-IIR protein. IGF2R encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of
ImmunogenImmunogen: Synthesized peptide derived from human IGF-IIR around the non-phosphorylation site of S2484
Other Names[Rabbit IGF-IIR; IGF2R; MPRI; Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor]
Gene, Accession #[IGF-IIR], Gene ID: 3482, NCBI: NP_000867.2, UniProt: P11717
Catalog #MBS9705493
Price$130, $220, $325
Order / More InfoIGF-IIR Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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