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Antigenic Specificity | PQBP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species (PubMed: 23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit. |
Immunogen | Immunogen: Recombinant Human Polyglutamine-binding protein 1 protein (2-265AA) |
Other Names | [Polyglutamine-binding protein 1; PQBP-1; 38 kDa nuclear protein containing a WW domain; Npw38; Polyglutamine tract-binding protein 1; PQBP1; NPW38; JM26] |
Gene, Accession # | [PQBP1], Gene ID: 10084, NCBI: NP_001027553.1, UniProt: O60828 |
Catalog # | MBS7048915 |
Price | $160, $235 |
Order / More Info | PQBP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |