PQBP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPQBP1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionProbably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species (PubMed: 23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
ImmunogenImmunogen: Recombinant Human Polyglutamine-binding protein 1 protein (2-265AA)
Other Names[Polyglutamine-binding protein 1; PQBP-1; 38 kDa nuclear protein containing a WW domain; Npw38; Polyglutamine tract-binding protein 1; PQBP1; NPW38; JM26]
Gene, Accession #[PQBP1], Gene ID: 10084, NCBI: NP_001027553.1, UniProt: O60828
Catalog #MBS7048915
Price$160, $235
Order / More InfoPQBP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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