FYN Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FYN |
| Clone | [1302CT390.118.237] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1,kappa |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This FYN antibody is generated from a mouse immunized with a recombinant preotein from human FYN. Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motility through phosphorylation of CTNNB1 (beta-catenin) and CTNND1 (delta- catenin). Regulates cytoskele |
| Immunogen | n/a |
| Other Names | [Tyrosine-protein kinase Fyn; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-Fyn; FYN] |
| Gene, Accession # | [FYN], Gene ID: 2534, NCBI: NP_002028.1, UniProt: P06241 |
| Catalog # | MBS9200350 |
| Price | $165, $370 |
| Order / More Info | FYN Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kawakami T.,et al.Mol. Cell. Biol. 6:4195-4201(1986). Semba K.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:5459-5463(1986). Rigley K.,et al.J. Immunol. 154:1136-1145(1995). Goshima N.,et al.Nat. Methods 5:1011-1017(2008). Mungall A.J.,et al.Nature 425:805-811(2003). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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