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Antigenic Specificity | CD44 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for CD44 antigen(CD44) detection. Tested with WB, IHC-P in Human. Background: CD44 is also known as LHR or MC56. The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CD44(29-56aa RFAGVFHVEKNGRYSISRTEAADLCKAF), different from the related mouse and rat sequences by two amino acids. Ig Type: Rabbit IgG |
Other Names | [CD44 antigen; LHR; BA-1; CD 44; CD44; CD44 antigen; CD44 isoform RC; CD44 molecule (Indian blood group); CD44 molecule; CD44_HUMAN; CDw44; Cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECM III; ECMR III; ECMR-III; ECMRIII; Epican; Extracellular Matrix Receptor III; GP90 Lymphocyte Homing Adhesion Receptor; GP90 lymphocyte homing/adhesion receptor; HCAM; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan Sulfate Proteoglycan; Hermes Antigen; homing function and Indian blood group system; HSA; HUTCH I; HUTCH-I; HUTCH1; Hyaluronate Receptor; IN; Indian blood group; Inlu Related p80 Glycoprotein; lhr; Ly 24; MC56; MDU2; MDU3; MGC10468; MIC4; MUTCH I; MUTCH1; PGP 1; PGP-1; PGP-I; PGP1; Phagocytic Glycoprotein 1; Phagocytic glycoprotein I; Transmembrane glycoprotein; CD44 molecule (Indian blood group)], [CD44; CD44; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; LHR; MDU2; MDU3; MIC4; ECMR-III; PGP-1; PGP-I] |
Gene, Accession # | [CD44], Gene ID: 960, NCBI: NP_000601.3, UniProt: P16070 |
Catalog # | MBS177822 |
Price | $315 |
Order / More Info | CD44 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Fagan-Solis KD, et al. Challenging the roles of CD44 and lipolysis stimulated lipoprotein receptor in conveying Clostridium perfringens iota toxin cytotoxicity in breast cancer. Mol Cancer, 2014 Jul 2. 2. Zhang P, et al. CD44 variant, but not standard CD44 isoforms, mediate disassembly of endothelial VE-cadherin junction on metastatic melanoma cells. FEBS Lett, 2014 Dec 20. |